STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_3918Endothelin-converting enzyme 1; KEGG: ccs:CCNA_03619 zinc metalloprotease; PFAM: peptidase M13; Peptidase M13, neprilysin-like. (705 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.724
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
    0.571
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
    
 0.539
Cseg_4197
KEGG: ccs:CCNA_03801 prolyl endopeptidase family; PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller.
 
  
 0.499
Cseg_0277
Amino acid/peptide transporter; KEGG: ccs:CCNA_03524 di-/tripeptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region.
 
  
 0.494
Cseg_4198
Prolyl oligopeptidase; KEGG: ccs:CCNA_03802 hypothetical protein; PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller.
 
  
 0.492
Cseg_3920
KEGG: cak:Caul_5418 RND efflux system outer membrane lipoprotein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein.
       0.461
Cseg_3919
PFAM: secretion protein HlyD family protein; major facilitator superfamily MFS_1; KEGG: cak:Caul_5420 transporter, putative.
       0.453
Cseg_3917
PFAM: MaoC domain protein dehydratase; KEGG: ccs:CCNA_03613 3-hydroxybutyryl-CoA dehydratase.
       0.437
Cseg_0853
PFAM: peptidase M28; KEGG: cak:Caul_0655 peptidase M28.
  
  
 0.416
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.