STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_4093PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: ccs:CCNA_03725 ATP-dependent DNA ligase. (536 aa)    
Predicted Functional Partners:
Cseg_4133
KEGG: ccs:CCNA_03759 mRNA 3'-end processing factor.
 
 0.957
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
    
 0.941
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.915
Cseg_1389
PFAM: metallophosphoesterase; KEGG: ccs:CCNA_02122 putative ICC-like phosphoesterase.
 
   
 0.818
Cseg_1390
DEAD/H associated domain protein; KEGG: ccs:CCNA_02121 ATP-dependent helicase; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
 
    0.796
Cseg_1878
PFAM: Nucleotidyl transferase; KEGG: cak:Caul_4933 histidinol-phosphate phosphatase family protein.
  
 0.663
Cseg_2122
KEGG: ccs:CCNA_01899 DNA polymerase III, delta' subunit; TIGRFAM: DNA polymerase III, delta prime subunit.
   
 0.635
Cseg_0708
KEGG: ccs:CCNA_03318 cytosolic protein.
  
 
 0.560
Cseg_1391
SMART: helicase c2; KEGG: ccr:CC_2038 hypothetical protein.
   
 
 0.558
Cseg_1418
KEGG: ccs:CCNA_02090 exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase.
  
 
 0.544
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.