STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_4131KEGG: ccs:CCNA_03757 citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family. (361 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.981
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.970
Cseg_4132
PFAM: Citrate synthase; KEGG: ccs:CCNA_03758 citrate synthase.
 
  
 
0.966
Cseg_1969
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.960
Cseg_0131
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; KEGG: ccs:CCNA_03663 NADP-dependent malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase.
  
 0.933
Cseg_1074
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; KEGG: ccs:CCNA_02704 NADP-dependent malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase.
  
 0.933
Cseg_2193
TIGRFAM: citrate synthase I; KEGG: ccs:CCNA_01983 citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
  
 
0.920
Cseg_4092
KEGG: ccs:CCNA_03722 glutamate synthase (NADPH) large chain; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein.
 
  
 0.918
Cseg_1459
PFAM: aminotransferase class I and II; KEGG: ccs:CCNA_01603 aspartate aminotransferase.
 
 0.893
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.888
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.