STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmCHeme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (247 aa)    
Predicted Functional Partners:
Cseg_4181
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
 0.998
ccmA
Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
 0.996
ccmE
CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.995
Cseg_4186
Periplasmic protein thiol/disulfide oxidoreductase DsbE; KEGG: ccs:CCNA_03788 thiol:disulfide interchange protein TlpA; TIGRFAM: periplasmic protein thiol/disulphide oxidoreductase DsbE; PFAM: Redoxin domain protein.
 
  
 0.983
Cseg_1010
Cytochrome c-type biogenesis protein CcmF; KEGG: ccs:CCNA_02848 heme chaperone-apocytochrome heme-lyase; TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein.
 
  
 0.878
Cseg_1011
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
 
   
 0.866
Cseg_4185
Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
       0.785
Cseg_2861
PFAM: Redoxin domain protein; KEGG: ccs:CCNA_02293 thiol:disulfide interchange protein TlpA.
 
  
 0.619
Cseg_1805
KEGG: cak:Caul_3607 gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I.
 
   
 0.606
Cseg_0064
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
    0.593
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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