Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KGL30633.17-alpha-hydroxysteroid dehydrogenase; Acts on the hydroxyl group at position 7 of the steroid frame; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)    
Predicted Functional Partners:
dapA
4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
 0.837
KGL31407.1
acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.819
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.789
KGL31489.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.778
KGL31612.1
Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.778
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.764
KGL31194.1
FolB domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.753
fabD
Malonyl CoA-ACP transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.749
msrA
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.725
KGL30634.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.711
Your Current Organism:
Helicobacter trogontum
NCBI taxonomy Id: 50960
Other names: ATCC 700114, CCUG 49050, Flexispira taxon 6, H. trogontum, Helicobacter sp. ATCC 43966, Helicobacter sp. ATCC 43968, Helicobacter sp. ATCC 49310, LRB 8581
Server load: low (24%) [HD]