Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KGL31889.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)    
Predicted Functional Partners:
KGL31874.1
Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
frdB
Part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.914
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.900
KGL30983.1
2-hydroxyacid dehydrogenase; Involved in the metabolism of aromatic amino acids; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.891
KGL31212.1
Cb-type cytochrome C oxidase subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
  
 0.890
KGL30905.1
Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.885
KGL30808.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.876
KGL30290.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.876
KGL30183.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.876
KGL31590.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.872
Your Current Organism:
Helicobacter trogontum
NCBI taxonomy Id: 50960
Other names: ATCC 700114, CCUG 49050, Flexispira taxon 6, H. trogontum, Helicobacter sp. ATCC 43966, Helicobacter sp. ATCC 43968, Helicobacter sp. ATCC 49310, LRB 8581
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