Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (304 aa)    
Predicted Functional Partners:
KGL31158.1
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.594
KGL30970.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.556
KGL31493.1
Guanosine monophosphate synthetase GuaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.546
KGL31480.1
Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family.
   
 
 0.541
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.527
msrA
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.515
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
 0.508
gabD
Succinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.486
KGL31578.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.486
KGL31614.1
Site-specific recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.478
Your Current Organism:
Helicobacter trogontum
NCBI taxonomy Id: 50960
Other names: ATCC 700114, CCUG 49050, Flexispira taxon 6, H. trogontum, Helicobacter sp. ATCC 43966, Helicobacter sp. ATCC 43968, Helicobacter sp. ATCC 49310, LRB 8581
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