node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ETZ19298.1 | ETZ19480.1 | N824_11190 | N824_12115 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.930 |
ETZ19298.1 | ETZ19983.1 | N824_11190 | N824_07165 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.954 |
ETZ19298.1 | ETZ21050.1 | N824_11190 | N824_02745 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.650 |
ETZ19298.1 | ETZ21559.1 | N824_11190 | N824_27880 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.570 |
ETZ19298.1 | adk | N824_11190 | N824_17005 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.955 |
ETZ19298.1 | apt | N824_11190 | N824_06490 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.916 |
ETZ19298.1 | gmk | N824_11190 | N824_11945 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.921 |
ETZ19298.1 | guaA | N824_11190 | N824_06090 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.928 |
ETZ19298.1 | guaB | N824_11190 | N824_19480 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.920 |
ETZ19298.1 | purH | N824_11190 | N824_06625 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.911 |
ETZ19480.1 | ETZ19298.1 | N824_12115 | N824_11190 | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.930 |
ETZ19480.1 | ETZ19983.1 | N824_12115 | N824_07165 | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.930 |
ETZ19480.1 | apt | N824_12115 | N824_06490 | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.930 |
ETZ19983.1 | ETZ19298.1 | N824_07165 | N824_11190 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.954 |
ETZ19983.1 | ETZ19480.1 | N824_07165 | N824_12115 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.930 |
ETZ19983.1 | ETZ21559.1 | N824_07165 | N824_27880 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.870 |
ETZ19983.1 | adk | N824_07165 | N824_17005 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.536 |
ETZ19983.1 | apt | N824_07165 | N824_06490 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.955 |
ETZ19983.1 | guaA | N824_07165 | N824_06090 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.593 |
ETZ19983.1 | guaB | N824_07165 | N824_19480 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.535 |