node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ETZ19689.1 | ETZ19691.1 | N824_09465 | N824_09475 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.995 |
ETZ19689.1 | ETZ23289.1 | N824_09465 | N824_17660 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.981 |
ETZ19689.1 | ETZ23291.1 | N824_09465 | N824_17670 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.869 |
ETZ19689.1 | ETZ24624.1 | N824_09465 | N824_13995 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Malic enzyme; NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.882 |
ETZ19689.1 | fumC | N824_09465 | N824_09780 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.969 |
ETZ19689.1 | gltA | N824_09465 | N824_22475 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the citrate synthase family. | 0.876 |
ETZ19689.1 | sdhA | N824_09465 | N824_09470 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.999 |
ETZ19689.1 | sdhA-2 | N824_09465 | N824_17665 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.998 |
ETZ19689.1 | sucC | N824_09465 | N824_18950 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | malate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.982 |
ETZ19689.1 | sucD | N824_09465 | N824_06990 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | succinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.986 |
ETZ19691.1 | ETZ19689.1 | N824_09475 | N824_09465 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.995 |
ETZ19691.1 | ETZ23289.1 | N824_09475 | N824_17660 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.881 |
ETZ19691.1 | ETZ23291.1 | N824_09475 | N824_17670 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.981 |
ETZ19691.1 | sdhA | N824_09475 | N824_09470 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.996 |
ETZ19691.1 | sdhA-2 | N824_09475 | N824_17665 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.985 |
ETZ19691.1 | sucC | N824_09475 | N824_18950 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | malate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.883 |
ETZ19691.1 | sucD | N824_09475 | N824_06990 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | succinyl-CoA synthetase subsunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.883 |
ETZ23289.1 | ETZ19689.1 | N824_17660 | N824_09465 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.981 |
ETZ23289.1 | ETZ19691.1 | N824_17660 | N824_09475 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.881 |
ETZ23289.1 | ETZ23291.1 | N824_17660 | N824_17670 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.996 |