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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBC7Ubiquitin-conjugating enzyme E2 7; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)    
Predicted Functional Partners:
UBA1
E1 ubiquitin-activating protein; Belongs to the ubiquitin-activating E1 family.
    
 0.964
HRD1
E3 ubiquitin-protein ligase hrd1.
    
 
 0.956
EMC3
ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.
    
 
 0.931
MPDQ_001711
ER membrane protein complex subunit 4; Belongs to the EMC4 family.
    
   0.922
CYC3
Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
    
0.897
MPDQ_006487
Uncharacterized protein.
 
  
 0.867
MPDQ_001722
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
0.865
MPDQ_005500
UBX domain-containing protein.
   
 
 0.861
MPDQ_007210
E2_bind domain-containing protein.
    
 0.855
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
 
  
 0.855
Your Current Organism:
Monascus purpureus
NCBI taxonomy Id: 5098
Other names: ATCC 16361 [[Monascus araneosus]], ATCC 16365, ATCC 16367 [[Monascus rubiginosus]], ATCC 16426, CBS 109.07, CBS 284.34 [[Monascus araneosus]], CBS 288.34 [[Monascus rubiginosus]], CECT 2955, FRR 2190 [[Monascus araneosus]], IFO 4482 [[Monascus araneosus]], IFO 4484 [[Monascus rubiginosus]], IFO 4513, IMI 210765, M. purpureus, Monascus albidus, Monascus anka, Monascus araneosus, Monascus purpurea, Monascus rubiginosus
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