STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HXK1_2Phosphotransferase. (490 aa)    
Predicted Functional Partners:
GLK1
Phosphotransferase.
  
 
0.960
PGI1
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 
 0.941
MPDQ_003361
Uncharacterized protein.
     
 0.930
PGM5
Phosphoglucomutase-5; Belongs to the phosphohexose mutase family.
   
 
 0.927
PFK1
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
   
 
 0.926
ZWF1
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
 
 0.911
FBA1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
   
 
 0.910
FBP1
Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family.
   
 
 0.906
GNA1
Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily.
   
 0.904
PGM3_1
Phosphoglucomutase-3; Belongs to the phosphohexose mutase family.
 
 
 
 0.903
Your Current Organism:
Monascus purpureus
NCBI taxonomy Id: 5098
Other names: ATCC 16361 [[Monascus araneosus]], ATCC 16365, ATCC 16367 [[Monascus rubiginosus]], ATCC 16426, CBS 109.07, CBS 284.34 [[Monascus araneosus]], CBS 288.34 [[Monascus rubiginosus]], CECT 2955, FRR 2190 [[Monascus araneosus]], IFO 4482 [[Monascus araneosus]], IFO 4484 [[Monascus rubiginosus]], IFO 4513, IMI 210765, M. purpureus, Monascus albidus, Monascus anka, Monascus araneosus, Monascus purpurea, Monascus rubiginosus
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