STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPDQ_007622BRCT domain-containing protein. (1458 aa)    
Predicted Functional Partners:
MPDQ_000909
Uncharacterized protein.
    
 0.990
MPDQ_008090
Uncharacterized protein.
    
 
 0.988
MEC1
Serine/threonine-protein kinase M1; Belongs to the PI3/PI4-kinase family.
    
 0.982
TEL1
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 0.972
HTA1
Histone H2A; Belongs to the histone H2A family.
    
 0.963
MPDQ_003864
Uncharacterized protein.
    
 0.956
KU70
ATP-dependent DNA helicase II subunit 1.
    
 0.951
MPDQ_004852
3'-5' exonuclease domain-containing protein.
   
 
 0.950
CHK1
Chk1 protein kinase.
    
 
 0.948
MPDQ_002639
BZIP domain-containing protein.
    
  0.939
Your Current Organism:
Monascus purpureus
NCBI taxonomy Id: 5098
Other names: ATCC 16361 [[Monascus araneosus]], ATCC 16365, ATCC 16367 [[Monascus rubiginosus]], ATCC 16426, CBS 109.07, CBS 284.34 [[Monascus araneosus]], CBS 288.34 [[Monascus rubiginosus]], CECT 2955, FRR 2190 [[Monascus araneosus]], IFO 4482 [[Monascus araneosus]], IFO 4484 [[Monascus rubiginosus]], IFO 4513, IMI 210765, M. purpureus, Monascus albidus, Monascus anka, Monascus araneosus, Monascus purpurea, Monascus rubiginosus
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.