STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPDQ_000304Uncharacterized protein. (465 aa)    
Predicted Functional Partners:
GCD11
Eukaryotic translation initiation factor 2 subunit gamma.
 
  
  0.933
DOT1
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.928
SET2
Histone methyltransferase set2; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
    
0.917
SET9
Histone-lysine N-methyltransferase set9.
     
 0.913
SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
  
  
0.907
HHT1
Histone H3; Belongs to the histone H3 family.
   
 0.903
CSE4
Centromeric DNA-binding histone H3-like protein cse4.
   
 0.903
MPDQ_004755
Chromo domain-containing protein.
   
 0.901
MPDQ_002480
Uncharacterized protein.
  
  
0.897
MPDQ_004883
Chromo domain-containing protein.
   
 0.894
Your Current Organism:
Monascus purpureus
NCBI taxonomy Id: 5098
Other names: ATCC 16361 [[Monascus araneosus]], ATCC 16365, ATCC 16367 [[Monascus rubiginosus]], ATCC 16426, CBS 109.07, CBS 284.34 [[Monascus araneosus]], CBS 288.34 [[Monascus rubiginosus]], CECT 2955, FRR 2190 [[Monascus araneosus]], IFO 4482 [[Monascus araneosus]], IFO 4484 [[Monascus rubiginosus]], IFO 4513, IMI 210765, M. purpureus, Monascus albidus, Monascus anka, Monascus araneosus, Monascus purpurea, Monascus rubiginosus
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.