STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESA1Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (501 aa)    
Predicted Functional Partners:
MPDQ_004852
3'-5' exonuclease domain-containing protein.
    
 0.988
EPL1
Enhancer of polycomb-like protein.
    
 0.986
MPDQ_007471
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.971
MEAF6
Chromatin modification-protein meaf6.
    
 0.968
MPDQ_003545
Chromatin modification-related protein.
    
 0.964
HHF1_2
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.962
SWC4
Swr complex subunit.
   
 0.952
ARP4
NuA4 histone acetyltransferase subunit; Belongs to the actin family.
   
 0.946
EAF3
Esa1p-associated factor.
    
 0.942
EAF1
Chromatin modification-protein VID21.
    
 0.941
Your Current Organism:
Monascus purpureus
NCBI taxonomy Id: 5098
Other names: ATCC 16361 [[Monascus araneosus]], ATCC 16365, ATCC 16367 [[Monascus rubiginosus]], ATCC 16426, CBS 109.07, CBS 284.34 [[Monascus araneosus]], CBS 288.34 [[Monascus rubiginosus]], CECT 2955, FRR 2190 [[Monascus araneosus]], IFO 4482 [[Monascus araneosus]], IFO 4484 [[Monascus rubiginosus]], IFO 4513, IMI 210765, M. purpureus, Monascus albidus, Monascus anka, Monascus araneosus, Monascus purpurea, Monascus rubiginosus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.