STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPDQ_004647Uncharacterized protein. (369 aa)    
Predicted Functional Partners:
IPL1
Spindle assembly checkpoint kinase; Belongs to the protein kinase superfamily.
   
 0.902
CYC1_2
Iso-1-cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
    
 0.879
MPDQ_006968
Uncharacterized protein.
    
 0.879
MPDQ_003515
Uncharacterized protein.
   
 0.849
MPDQ_005220
Uncharacterized protein.
   
 
 0.828
UBA4
Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
    
 0.727
MDE1
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
    
 0.696
NDUFA12
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    
   0.662
NDH51
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.
    
   0.662
NUO21
NADH:ubiquinone oxidoreductase 21kD subunit.
    
   0.662
Your Current Organism:
Monascus purpureus
NCBI taxonomy Id: 5098
Other names: ATCC 16361 [[Monascus araneosus]], ATCC 16365, ATCC 16367 [[Monascus rubiginosus]], ATCC 16426, CBS 109.07, CBS 284.34 [[Monascus araneosus]], CBS 288.34 [[Monascus rubiginosus]], CECT 2955, FRR 2190 [[Monascus araneosus]], IFO 4482 [[Monascus araneosus]], IFO 4484 [[Monascus rubiginosus]], IFO 4513, IMI 210765, M. purpureus, Monascus albidus, Monascus anka, Monascus araneosus, Monascus purpurea, Monascus rubiginosus
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.