STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_15840Phosphotransferase. (197 aa)    
Predicted Functional Partners:
NECAME_16862
Phosphotransferase.
 
     0.880
NECAME_16422
Glucose-6-phosphate isomerase; Belongs to the GPI family.
   
 
 0.634
NECAME_00358
Malate synthase A.
   
  
 0.516
NECAME_03476
AMP-binding enzyme.
   
  
 0.497
NECAME_01086
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
   
  
 0.488
NECAME_08012
Phosphofructokinase.
   
  
 0.488
NECAME_08877
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II.
   
 
 0.473
NECAME_05853
Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.
   
 
 0.423
NECAME_05410
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
 
 0.409
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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