STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_04526PHD-type domain-containing protein. (489 aa)    
Predicted Functional Partners:
NECAME_02759
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.992
NECAME_14433
SAP30_Sin3_bdg domain-containing protein.
   
 0.988
NECAME_06952
RNA polymerase Rpb3/Rpb11 dimerization domain protein.
   
 0.987
NECAME_07844
RNA polymerase Rpb5 domain protein.
   
 0.979
NECAME_02903
RNA polymerase I specific transcription initiation factor RRN3.
   
 0.974
NECAME_11388
RNA polymerase Rpb1, domain 2.
   
 0.972
NECAME_11389
RNA_pol_Rpb1_5 domain-containing protein.
   
 0.972
NECAME_04274
DNA-directed RNA polymerase subunit N.
   
 0.963
NECAME_03482
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
   
 0.962
NECAME_03343
RNA polymerase Rpb3/Rpb11 dimerization domain protein.
   
 0.928
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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