STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_19202Uncharacterized protein. (72 aa)    
Predicted Functional Partners:
NECAME_02884
DNA mismatch repair protein.
   
 0.929
NECAME_08781
Uncharacterized protein; Belongs to the RecA family.
  
 0.928
NECAME_08628
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.926
NECAME_00196
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.903
NECAME_00524
AAA_12 domain-containing protein.
   
 0.878
NECAME_07595
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.878
NECAME_01401
DNA mismatch repair protein.
   
 0.864
NECAME_09543
Uncharacterized protein.
  
 0.862
NECAME_06630
MutS domain V protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.860
NECAME_06631
DNA_MISMATCH_REPAIR_2 domain-containing protein.
   
 0.860
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.