STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_04366Sema domain protein; Belongs to the semaphorin family. (618 aa)    
Predicted Functional Partners:
NECAME_04967
IPT/TIG domain-containing protein.
  
 
 0.685
NECAME_04965
Sema domain protein.
  
 
 0.640
NECAME_15599
Sema domain-containing protein.
    
 0.578
NECAME_12513
IPT/TIG domain protein.
    
 0.578
NECAME_12512
Plexin cytoplasmic region.
    
 0.578
NECAME_04966
Plexin repeat-containing domain protein.
    
 0.547
NECAME_04968
Plexin_cytopl domain-containing protein.
    
 0.547
NECAME_19632
Plexin cytoplasmic region.
    
 0.547
NECAME_11256
Protein kinase domain-containing protein.
     
 0.486
NECAME_00245
I/LWEQ domain protein.
     
 0.454
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.