STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_13394Cyclin domain protein; Belongs to the cyclin family. (285 aa)    
Predicted Functional Partners:
NECAME_01012
Retinoblastoma-associated protein B domain protein.
    
 0.922
NECAME_01013
DUF3452 domain-containing protein.
    
 0.922
NECAME_13755
Cyclin-dependent kinase inhibitor.
   
 0.922
NECAME_13756
Cyclin-dependent kinase inhibitor.
   
 0.902
NECAME_00743
Kinase domain protein; Belongs to the protein kinase superfamily.
   
 0.888
NECAME_17028
Cullin family protein; Belongs to the cullin family.
    
 0.836
NECAME_04651
Protein kinase domain-containing protein.
   
 0.832
NECAME_04652
Protein kinase domain-containing protein.
   
 0.832
NECAME_12986
Kinase domain protein.
   
 0.832
NECAME_01242
Kinase domain protein; Belongs to the protein kinase superfamily.
   
 0.832
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.