STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_12520FATC domain protein; Belongs to the PI3/PI4-kinase family. (290 aa)    
Predicted Functional Partners:
NECAME_14599
Protein kinase domain-containing protein.
    
 0.913
NECAME_08628
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.887
NECAME_07577
RPA_C domain-containing protein.
   
 0.880
NECAME_09581
Uncharacterized protein.
    
 0.870
NECAME_09582
Kinase domain protein; Belongs to the protein kinase superfamily.
    
 0.870
NECAME_12459
Kinase domain protein; Belongs to the protein kinase superfamily.
    
 
 0.861
NECAME_10309
Rad17 cell cycle checkpoint protein.
   
 0.820
NECAME_15264
Uncharacterized protein.
    
 0.816
NECAME_15262
BRCT domain-containing protein.
    
 0.816
NECAME_02538
Replication factor-A domain protein.
    
 0.804
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.