NECAME_03820 protein (Necator americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NECAME_03820

Small ubiquitin-related modifier. (96 aa)

Predicted Functional Partners:

NECAME_13099

0.998

NECAME_12880

0.992

NECAME_08049

0.987

NECAME_00893

0.983

NECAME_07851

0.978

NECAME_08935

0.968

NECAME_08936

0.968

NECAME_07595

0.965

NECAME_12669

0.950

NECAME_12670

0.949

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00893	NECAME_03820	W2SNE5	W2T289	Ulp1 protease family, catalytic domain protein.	Small ubiquitin-related modifier.	0.983
NECAME_00893	NECAME_07851	W2SNE5	W2TNK8	Ulp1 protease family, catalytic domain protein.	Uncharacterized protein.	0.575
NECAME_00893	NECAME_08049	W2SNE5	W2TMW9	Ulp1 protease family, catalytic domain protein.	ThiF family protein.	0.689
NECAME_00893	NECAME_08935	W2SNE5	W2TI20	Ulp1 protease family, catalytic domain protein.	Uncharacterized protein.	0.793
NECAME_00893	NECAME_08936	W2SNE5	W2TIG4	Ulp1 protease family, catalytic domain protein.	Uncharacterized protein.	0.793
NECAME_00893	NECAME_12669	W2SNE5	W2SZ63	Ulp1 protease family, catalytic domain protein.	SAP domain-containing protein.	0.599
NECAME_00893	NECAME_12670	W2SNE5	W2T001	Ulp1 protease family, catalytic domain protein.	SP-RING-type domain-containing protein.	0.599
NECAME_00893	NECAME_12880	W2SNE5	W2SY74	Ulp1 protease family, catalytic domain protein.	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.	0.696
NECAME_00893	NECAME_13099	W2SNE5	W2SX01	Ulp1 protease family, catalytic domain protein.	Ubiquitin--protein ligase; Belongs to the ubiquitin-conjugating enzyme family.	0.600
NECAME_03820	NECAME_00893	W2T289	W2SNE5	Small ubiquitin-related modifier.	Ulp1 protease family, catalytic domain protein.	0.983
NECAME_03820	NECAME_07595	W2T289	W2TMK5	Small ubiquitin-related modifier.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.965
NECAME_03820	NECAME_07851	W2T289	W2TNK8	Small ubiquitin-related modifier.	Uncharacterized protein.	0.978
NECAME_03820	NECAME_08049	W2T289	W2TMW9	Small ubiquitin-related modifier.	ThiF family protein.	0.987
NECAME_03820	NECAME_08935	W2T289	W2TI20	Small ubiquitin-related modifier.	Uncharacterized protein.	0.968
NECAME_03820	NECAME_08936	W2T289	W2TIG4	Small ubiquitin-related modifier.	Uncharacterized protein.	0.968
NECAME_03820	NECAME_12669	W2T289	W2SZ63	Small ubiquitin-related modifier.	SAP domain-containing protein.	0.950
NECAME_03820	NECAME_12670	W2T289	W2T001	Small ubiquitin-related modifier.	SP-RING-type domain-containing protein.	0.949
NECAME_03820	NECAME_12880	W2T289	W2SY74	Small ubiquitin-related modifier.	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.	0.992
NECAME_03820	NECAME_13099	W2T289	W2SX01	Small ubiquitin-related modifier.	Ubiquitin--protein ligase; Belongs to the ubiquitin-conjugating enzyme family.	0.998
NECAME_07595	NECAME_03820	W2TMK5	W2T289	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Small ubiquitin-related modifier.	0.965