NECAME_03647 protein (Necator americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NECAME_03647

Uncharacterized protein. (414 aa)

Predicted Functional Partners:

NECAME_14015

0.855

NECAME_06436

0.840

NECAME_03830

0.774

NECAME_10523

0.774

NECAME_17028

0.759

NECAME_02269

0.726

NECAME_13407

0.681

NECAME_06644

0.678

NECAME_06642

0.678

NECAME_03839

0.675

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_02269	NECAME_03647	W2TFQ5	W2T2T6	Putative RING-box protein 1.	Uncharacterized protein.	0.726
NECAME_02269	NECAME_03830	W2TFQ5	W2T2A0	Putative RING-box protein 1.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.633
NECAME_02269	NECAME_03839	W2TFQ5	W2T1I7	Putative RING-box protein 1.	Ribosomal protein L13; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.618
NECAME_02269	NECAME_10523	W2TFQ5	W2T981	Putative RING-box protein 1.	Kinase domain protein; Belongs to the protein kinase superfamily.	0.633
NECAME_02269	NECAME_13407	W2TFQ5	W2SWD0	Putative RING-box protein 1.	26S proteasome subunit P45 family protein; Belongs to the AAA ATPase family.	0.647
NECAME_02269	NECAME_14015	W2TFQ5	W2STH3	Putative RING-box protein 1.	Cullin family protein; Belongs to the cullin family.	0.992
NECAME_02269	NECAME_17028	W2TFQ5	W2TUJ8	Putative RING-box protein 1.	Cullin family protein; Belongs to the cullin family.	0.997
NECAME_03647	NECAME_02269	W2T2T6	W2TFQ5	Uncharacterized protein.	Putative RING-box protein 1.	0.726
NECAME_03647	NECAME_03830	W2T2T6	W2T2A0	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.774
NECAME_03647	NECAME_03839	W2T2T6	W2T1I7	Uncharacterized protein.	Ribosomal protein L13; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.675
NECAME_03647	NECAME_06436	W2T2T6	W2TU86	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.840
NECAME_03647	NECAME_06642	W2T2T6	W2TSW0	Uncharacterized protein.	RICTOR_N domain-containing protein.	0.678
NECAME_03647	NECAME_06644	W2T2T6	W2TS13	Uncharacterized protein.	RICTOR_V domain-containing protein.	0.678
NECAME_03647	NECAME_10523	W2T2T6	W2T981	Uncharacterized protein.	Kinase domain protein; Belongs to the protein kinase superfamily.	0.774
NECAME_03647	NECAME_13407	W2T2T6	W2SWD0	Uncharacterized protein.	26S proteasome subunit P45 family protein; Belongs to the AAA ATPase family.	0.681
NECAME_03647	NECAME_14015	W2T2T6	W2STH3	Uncharacterized protein.	Cullin family protein; Belongs to the cullin family.	0.855
NECAME_03647	NECAME_17028	W2T2T6	W2TUJ8	Uncharacterized protein.	Cullin family protein; Belongs to the cullin family.	0.759
NECAME_03830	NECAME_02269	W2T2A0	W2TFQ5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Putative RING-box protein 1.	0.633
NECAME_03830	NECAME_03647	W2T2A0	W2T2T6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.774
NECAME_03830	NECAME_03839	W2T2A0	W2T1I7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ribosomal protein L13; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.501