STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_12038BRCA1 protein. (428 aa)    
Predicted Functional Partners:
NECAME_08628
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.867
NECAME_12459
Kinase domain protein; Belongs to the protein kinase superfamily.
   
 0.749
NECAME_11706
Uncharacterized protein.
    
 0.742
NECAME_07240
Meiotic recombinase Dmc1; Belongs to the RecA family.
   
 0.706
NECAME_15264
Uncharacterized protein.
   
 0.691
NECAME_15262
BRCT domain-containing protein.
   
 0.691
NECAME_00878
Uncharacterized protein.
   
 0.677
NECAME_08781
Uncharacterized protein; Belongs to the RecA family.
   
 0.677
NECAME_12265
Ubiquitin carboxyl-terminal hydrolase.
    
 0.670
NECAME_02898
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.663
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
Server load: low (26%) [HD]