STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_11660Poly [ADP-ribose] polymerase. (293 aa)    
Predicted Functional Partners:
NECAME_11975
Poly [ADP-ribose] polymerase.
  
  
 
0.901
NECAME_10812
Poly glycohydrolase.
  
 
 0.829
NECAME_18868
PARP alpha-helical domain-containing protein.
 
     0.782
NECAME_11467
Uncharacterized protein.
    
 
 0.668
NECAME_12620
DNA repair protein Rad4.
    
 0.658
NECAME_07577
RPA_C domain-containing protein.
   
 0.601
NECAME_05184
DNA repair protein.
     
 0.572
NECAME_10811
Uncharacterized protein.
    
 0.566
NECAME_01378
Ku70/Ku80 beta-barrel domain protein.
   
 
 0.564
NECAME_08628
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.523
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.