NECAME_03644 protein (Necator americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NECAME_03644

Cse1. (343 aa)

Predicted Functional Partners:

NECAME_03527

0.884

NECAME_03645

0.874

NECAME_14200

0.823

NECAME_00345

0.755

NECAME_03700

0.754

NECAME_07732

0.754

NECAME_09939

0.750

NECAME_05961

0.731

NECAME_19687

0.601

NECAME_10477

0.558

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00345	NECAME_03527	W2TD80	W2T3M3	Importin-beta protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.998
NECAME_00345	NECAME_03644	W2TD80	W2T3S2	Importin-beta protein.	Cse1.	0.755
NECAME_00345	NECAME_03645	W2TD80	W2T4I8	Importin-beta protein.	Importin-beta protein.	0.755
NECAME_00345	NECAME_03700	W2TD80	W2T1E1	Importin-beta protein.	Importin subunit alpha; Belongs to the importin alpha family.	0.537
NECAME_00345	NECAME_05961	W2TD80	W2TXR2	Importin-beta protein.	Uncharacterized protein.	0.681
NECAME_00345	NECAME_07732	W2TD80	W2TMG4	Importin-beta protein.	Uncharacterized protein.	0.537
NECAME_00345	NECAME_14200	W2TD80	W2SPM2	Importin-beta protein.	Importin subunit alpha; Belongs to the importin alpha family.	0.537
NECAME_00345	NECAME_19687	W2TD80	W2T1K6	Importin-beta protein.	HEAT repeat protein.	0.769
NECAME_03527	NECAME_00345	W2T3M3	W2TD80	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin-beta protein.	0.998
NECAME_03527	NECAME_03644	W2T3M3	W2T3S2	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Cse1.	0.884
NECAME_03527	NECAME_03645	W2T3M3	W2T4I8	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin-beta protein.	0.884
NECAME_03527	NECAME_03700	W2T3M3	W2T1E1	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin subunit alpha; Belongs to the importin alpha family.	0.789
NECAME_03527	NECAME_07732	W2T3M3	W2TMG4	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Uncharacterized protein.	0.789
NECAME_03527	NECAME_09939	W2T3M3	W2TC47	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Uncharacterized protein.	0.541
NECAME_03527	NECAME_14200	W2T3M3	W2SPM2	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin subunit alpha; Belongs to the importin alpha family.	0.799
NECAME_03527	NECAME_19687	W2T3M3	W2T1K6	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	HEAT repeat protein.	0.991
NECAME_03644	NECAME_00345	W2T3S2	W2TD80	Cse1.	Importin-beta protein.	0.755
NECAME_03644	NECAME_03527	W2T3S2	W2T3M3	Cse1.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.884
NECAME_03644	NECAME_03645	W2T3S2	W2T4I8	Cse1.	Importin-beta protein.	0.874
NECAME_03644	NECAME_03700	W2T3S2	W2T1E1	Cse1.	Importin subunit alpha; Belongs to the importin alpha family.	0.754