STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_03400Protein kinase domain-containing protein. (322 aa)    
Predicted Functional Partners:
NECAME_07119
Immunoglobulin I-set domain protein.
   
 0.822
NECAME_09201
Signal transducer and activator of transcription.
    
 0.764
NECAME_04660
CBL proto-oncogene, SH2-like domain protein.
    
 0.650
NECAME_00044
Ankyrin repeat protein.
    
 0.613
NECAME_00042
Uncharacterized protein.
    
 0.613
NECAME_00043
Uncharacterized protein.
    
 0.613
NECAME_18922
Uncharacterized protein.
    
 0.606
NECAME_07121
Variant SH3 domain protein.
    
 0.606
NECAME_07120
Uncharacterized protein.
    
 0.606
NECAME_09771
14-3-3 protein; Belongs to the 14-3-3 family.
   
 0.595
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.