STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_11490G-protein alpha subunit. (334 aa)    
Predicted Functional Partners:
NECAME_02871
Adenylate/guanylate cyclase catalytic domain protein.
    
 0.993
NECAME_04791
GGL domain protein.
   
 0.960
NECAME_02446
7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.948
NECAME_14758
Muscarinic acetylcholine receptor gar-3 family protein; Belongs to the G-protein coupled receptor 1 family.
     
 0.900
NECAME_00757
7 transmembrane receptor.
     
  0.900
NECAME_00755
WD domain, G-beta repeat protein.
   
 0.867
NECAME_06196
WD domain, G-beta repeat protein.
   
 0.867
NECAME_06197
Uncharacterized protein.
   
 0.809
NECAME_17454
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
 0.763
NECAME_00624
7 transmembrane receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.739
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.