STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_10818Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. (1114 aa)    
Predicted Functional Partners:
NECAME_14975
Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex.
 0.999
NECAME_09355
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.995
NECAME_09534
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 
 0.991
NECAME_01564
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 
 0.991
NECAME_08371
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.988
NECAME_09992
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.972
NECAME_05988
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 
 0.970
NECAME_05710
Iso_dh domain-containing protein.
  
 0.961
NECAME_10978
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.961
NECAME_17070
Putative isocitrate dehydrogenase, NAD-dependent.
  
 0.961
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.