STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_11348HAD hydrolase, family IA, variant 3. (232 aa)    
Predicted Functional Partners:
NECAME_17756
Aminotran_5 domain-containing protein.
    
 0.562
NECAME_16422
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.544
NECAME_10405
Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.503
NECAME_05853
Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.
   
 0.460
NECAME_15576
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Belongs to the phosphohexose mutase family.
  
 0.455
NECAME_14442
Aamy domain-containing protein.
  
 
 0.454
NECAME_09736
Uncharacterized protein.
  
 
 0.454
NECAME_09737
Alpha amylase, catalytic domain protein; Belongs to the glycosyl hydrolase 13 family.
  
 
 0.454
NECAME_09106
Alpha amylase, catalytic domain protein.
  
 
 0.454
NECAME_12568
Sua5/YciO/YrdC/YwlC family protein.
  
 
  0.451
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
Server load: low (22%) [HD]