STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_08949BolA-like protein; Belongs to the BolA/IbaG family. (277 aa)    
Predicted Functional Partners:
NECAME_00905
BolA-like protein; Belongs to the BolA/IbaG family.
   
 
 0.975
NECAME_10492
Monothiol glutaredoxin, Grx4 family.
  
 
 0.873
NECAME_09161
Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.
  
 
 0.873
NECAME_11335
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
    
 
 0.870
NECAME_00364
Iron-sulfur cluster assembly accessory protein.
   
 
 0.694
NECAME_13106
NifU-like protein.
   
 
 0.691
NECAME_05721
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
    
 
 0.673
NECAME_00744
Glycine cleavage T-protein barrel domain protein.
      
 0.650
NECAME_09523
FeS cluster assembly scaffold IscU; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
      
 0.648
NECAME_17110
Import inner membrane translocase subunit TIM9 domain protein.
   
  
 0.609
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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