STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_17649HAD hydrolase, family IA, variant 3. (719 aa)    
Predicted Functional Partners:
NECAME_15447
Oxidoreductase, short chain dehydrogenase/reductase family protein.
 
      0.667
NECAME_10717
SH3 domain protein.
     
 0.619
NECAME_10240
RING-type domain-containing protein.
     
 0.578
NECAME_00570
Pex2 / Pex12 amino terminal region.
     
 0.563
NECAME_12679
Peroxisomal membrane anchor protein conserved region.
   
 
 0.508
NECAME_15517
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.
    
 0.473
NECAME_15520
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.
    
 0.473
NECAME_19470
PDZ_6 domain-containing protein.
   
 
  0.468
NECAME_15552
Sodium:sulfate symporter transmembrane region.
    
 0.440
NECAME_15551
Uncharacterized protein.
    
 0.440
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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