STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_08251Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (241 aa)    
Predicted Functional Partners:
NECAME_06832
Pyridoxal kinase.
  
  
 0.846
NECAME_04063
Chaperonin GroS; Belongs to the GroES chaperonin family.
     
 0.683
NECAME_10844
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.
 
 
  
 0.658
NECAME_07514
SPFH/Band 7/PHB domain protein.
 
    
 0.655
NECAME_15499
Cys/Met metabolism PLP-dependent enzyme.
  
  
 0.585
NECAME_04408
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
  
 0.564
NECAME_02656
Putative ribosomal protein L29.
   
    0.524
NECAME_07420
Ribosomal protein L29.
   
    0.524
NECAME_08800
DAO domain-containing protein.
    
 0.512
NECAME_10434
Ribosomal protein L24.
   
    0.503
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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