STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_07832Cofilin/tropomyosin-type actin-binding protein. (167 aa)    
Predicted Functional Partners:
NECAME_11788
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.968
NECAME_07107
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.959
NECAME_07600
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.897
NECAME_13068
Uncharacterized protein.
     
 0.801
NECAME_16197
Actin.
   
 0.744
NECAME_03995
Variant SH3 domain protein.
     
 0.701
NECAME_06788
Profilin; Belongs to the profilin family.
    
 
 0.691
NECAME_01083
RHO protein GDP dissociation inhibitor.
   
 
 0.689
NECAME_04495
ADF-H domain-containing protein.
   
 
 0.675
NECAME_10164
WD domain, G-beta repeat protein.
    
 
 0.658
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.