STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_07240Meiotic recombinase Dmc1; Belongs to the RecA family. (345 aa)    
Predicted Functional Partners:
NECAME_08781
Uncharacterized protein; Belongs to the RecA family.
  
0.979
NECAME_00878
Uncharacterized protein.
   
 0.969
NECAME_01737
ERCC4 domain protein.
   
 0.897
NECAME_08628
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.893
NECAME_07595
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.882
NECAME_03630
Type IIB DNA topoisomerase.
    
 0.865
NECAME_14544
ATPase, AAA family; Belongs to the AAA ATPase family.
  
 
 0.833
NECAME_15057
Uncharacterized protein.
  
 
 0.832
NECAME_01313
Protein, SNF2 family.
  
 
 0.832
NECAME_00524
AAA_12 domain-containing protein.
   
 0.815
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.