STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_06873Uncharacterized protein. (98 aa)    
Predicted Functional Partners:
NECAME_04943
Uncharacterized protein.
    
 0.921
NECAME_13647
HAD hydrolase, family IA, variant 3.
  
 
 0.875
NECAME_00036
Methylthioribulose-1-phosphate dehydratase.
  
 
 0.800
NECAME_05285
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.786
NECAME_12161
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.786
NECAME_01073
Delta l-pyrroline-5-carboxylate synthetase.
  
  
 0.729
NECAME_18417
Aldolase_II domain-containing protein.
  
 
 0.661
NECAME_18760
Aldolase_II domain-containing protein.
  
 
 0.661
NECAME_18588
Uncharacterized protein.
  
 
 0.661
NECAME_08058
Class II Aldolase and Adducin domain protein.
  
 
 0.661
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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