STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_17118Piwi domain protein. (474 aa)    
Predicted Functional Partners:
NECAME_01620
NHL repeat protein.
    
  0.907
NECAME_16688
Nsp1-like region.
   
 
  0.571
NECAME_14275
RNase3 domain protein.
   
 0.542
NECAME_14274
Uncharacterized protein.
   
 0.542
NECAME_14273
Double stranded RNA binding domain protein; Belongs to the helicase family. Dicer subfamily.
   
 0.542
NECAME_00996
PAZ domain protein.
 
  
  0.531
NECAME_15259
Piwi domain-containing protein.
  
  
  0.522
NECAME_12816
DRBM domain-containing protein.
    
 0.487
NECAME_12817
DRBM domain-containing protein.
    
 0.487
NECAME_04517
Uncharacterized protein.
    
 0.470
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.