STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_06935Hypoxia induced protein conserved region. (133 aa)    
Predicted Functional Partners:
NECAME_00188
Cytochrome c oxidase subunit Vb.
   
 
 0.940
NECAME_03890
Cytochrome c oxidase subunit 6A, mitochondrial.
   
 
 0.866
NECAME_11329
Cytochrome c oxidase subunit 6A, mitochondrial.
   
 
 0.866
NECAME_11330
Cytochrome c oxidase subunit VIa; Belongs to the cytochrome c oxidase subunit 6A family.
   
 
 0.866
NECAME_15612
Cytochrome oxidase c subunit VIb.
   
 
 0.822
NECAME_06299
PRORP domain-containing protein.
   
 
 0.822
NECAME_00827
Peptidase, M16 family; Belongs to the peptidase M16 family.
   
 
 0.744
NECAME_12991
Peptidase, M16 family.
   
 
 0.744
NECAME_13280
Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
   
  
 0.700
NECAME_09395
Cytochrome c oxidase subunit Va.
   
  
 0.642
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.