STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AO090102000521Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (327 aa)    
Predicted Functional Partners:
AO090011000719
MIF4G domain-containing protein.
    
 0.919
AO090010000225
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
     
0.910
AO090026000289
GYF domain-containing protein.
    
 
 0.873
AO090003000365
RBR-type E3 ubiquitin transferase.
    
 0.707
AO090010000025
Uncharacterized protein.
    
 
 0.622
AO090012000784
Uncharacterized protein.
    
 
 0.622
MED19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.622
tif1
ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
   
 
 0.602
AO090003000953
Tr-type G domain-containing protein.
      
 0.585
AO090023000716
Uncharacterized protein.
    
 0.569
Your Current Organism:
Aspergillus oryzae
NCBI taxonomy Id: 510516
Other names: A. oryzae RIB40, Aspergillus oryzae RIB40
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.