STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbhAProbable 1,4-beta-D-glucan cellobiohydrolase A; The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose. (455 aa)    
Predicted Functional Partners:
AO090038000439
Glucanase; Belongs to the glycosyl hydrolase family 6.
  
  
 0.976
eglB
Probable endo-beta-1,4-glucanase B; Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates (By similarity).
     
 0.972
xlnR
Xylanolytic transcriptional activator xlnR; Transcriptional activator of the xylanolytic system. Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose. Binds to the DNA sequence 5'-GGNTAAA-3'.
    
 0.957
AO090011000715
CBM1 domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
     
 0.956
bglA
Probable beta-glucosidase A; Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity). Belongs to the glycosyl hydrolase 3 family.
    
 0.920
AO090003000497
Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family.
   
 
 0.917
celB
Endo-beta-1,4-glucanase celB; Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates. Belongs to the glycosyl hydrolase 7 (cellulase C) family.
  
  
0.909
AO090001000348
Glucanase; Belongs to the glycosyl hydrolase 7 (cellulase C) family.
  
  
0.902
AO090003001342
CBM_X2 domain-containing protein.
     
  0.900
AO090103000127
Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family.
    
 0.852
Your Current Organism:
Aspergillus oryzae
NCBI taxonomy Id: 510516
Other names: A. oryzae RIB40, Aspergillus oryzae RIB40
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