Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
guaDGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (441 aa)    
Predicted Functional Partners:
xdhA
FAD-binding molybdopterin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.991
xdhB
Aldehyde oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.987
xdhC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.951
pgeF
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.804
uraH
5-hydroxyisourate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
   
 0.750
uraD
OHCU decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.720
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
   
 
  0.650
ALO37139.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.625
puuE
Allantoinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.620
ALO37107.1
Heavy metal resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.519
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Achromobacter sp. ATCC8750, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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