Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ALO37113.1Nicotinate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.817
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.808
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.633
flgD
Flagellar basal body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.
    
   0.633
fliE
Flagellar hook-basal body protein FliE; Forms a junction between the M-ring and FlgB during flagella biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.633
ALO37748.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.618
ALO37632.1
Thiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.610
guaB
Guanosine monophosphate reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.602
flgG
Flagellar basal-body rod protein FlgG; Makes up the distal portion of the flagellar basal body rod; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.597
ALO40055.1
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.595
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Achromobacter sp. ATCC8750, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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