Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccoPCytochrome oxidase subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (305 aa)    
Predicted Functional Partners:
ccoO
Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
ccoN
Cytochrome C oxidase Cbb3; CcoN; FixN; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family.
 
 0.999
ccoG
Cytochrome c oxidase accessory protein CcoG; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.997
ALO37170.1
Cytochrome oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.997
coxB
Cytochrome C oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 0.997
petA
Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 0.996
ALO37590.1
Cytochrome C oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
ALO38183.1
Cytochrome C oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
ALO39639.1
Cytochrome C oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
ALO38927.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.987
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Achromobacter sp. ATCC8750, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
Server load: medium (42%) [HD]