STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dctAC4-dicarboxylate ABC transporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (429 aa)    
Predicted Functional Partners:
ALO39162.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.679
ALO37251.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.577
sdhD
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.564
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.541
ALO37504.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.523
ALO37744.1
Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.502
ALO37919.1
Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.502
ALO40306.1
Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.502
ALO39977.1
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.463
hflC
Protease modulator HflC; HflC and HflK could regulate a protease.
    
 0.462
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Achromobacter sp. ATCC8750, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.