Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hyiHydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family. (262 aa)    
Predicted Functional Partners:
gcl
Glyoxylate carboligase; Catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
 
 
 0.982
ALO38175.1
2-hydroxy-3-oxopropionate reductase; NADH-dependent; catalyzed the reversible formation of glycerate from tartronate semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.921
ALO37312.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.767
ALO39641.1
Class V aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.695
ALO37325.1
2-hydroxy-3-oxopropionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.646
ALO38912.1
2-hydroxy-3-oxopropionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.646
ALO38176.1
Hydroxypyruvate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.582
ALO38172.1
LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
 
     0.546
hpaI
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
     
  0.543
hpaI-2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
     
  0.543
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Achromobacter sp. ATCC8750, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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