Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (416 aa)    
Predicted Functional Partners:
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.993
ALO38625.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.893
ALO40138.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.893
ALO38692.1
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family.
   
 
  0.866
ALO39671.1
Class V aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.832
ALO38259.1
Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.693
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
    
 
 0.684
ALO37225.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 
  0.650
ALO39216.1
2-aminobenzoate-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.565
ALO38629.1
Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.554
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Achromobacter sp. ATCC8750, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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