STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (576 aa)    
Predicted Functional Partners:
hutH
Catalyzes the degradation of histidine to urocanate and ammmonia; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
hutI
Imidazolonepropionase; Catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 0.999
ALO39643.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.913
hutC
Histidine utilization repressor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.839
hutG
N-formylglutamate deformylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.716
ALO40387.1
Catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.701
ALO38849.1
Histidine utilization protein HutD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.564
ALO37750.1
Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
     
 0.538
ALO38732.1
Glycine/betaine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.458
ALO39397.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.446
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Achromobacter sp. ATCC8750, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.