| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALO39259.1 | ALO39260.1 | UZ73_13895 | UZ73_13900 | Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0307 family. | 0.883 |
| ALO39259.1 | pmbA | UZ73_13895 | UZ73_13905 | Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.664 |
| ALO39260.1 | ALO39259.1 | UZ73_13900 | UZ73_13895 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0307 family. | Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.883 |
| ALO39260.1 | pmbA | UZ73_13900 | UZ73_13905 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0307 family. | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.650 |
| ALO39262.1 | pmbA | UZ73_13910 | UZ73_13905 | ABC transporter substrate-binding protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system. | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.441 |
| mpl | pmbA | UZ73_13745 | UZ73_13905 | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.689 |
| mreD | pmbA | UZ73_13550 | UZ73_13905 | Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.483 |
| mreD | zapD | UZ73_13550 | UZ73_13420 | Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.549 |
| pmbA | ALO39259.1 | UZ73_13905 | UZ73_13895 | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.664 |
| pmbA | ALO39260.1 | UZ73_13905 | UZ73_13900 | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0307 family. | 0.650 |
| pmbA | ALO39262.1 | UZ73_13905 | UZ73_13910 | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter substrate-binding protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system. | 0.441 |
| pmbA | mpl | UZ73_13905 | UZ73_13745 | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.689 |
| pmbA | mreD | UZ73_13905 | UZ73_13550 | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.483 |
| pmbA | tldD | UZ73_13905 | UZ73_02875 | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
| pmbA | zapD | UZ73_13905 | UZ73_13420 | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.466 |
| tldD | pmbA | UZ73_02875 | UZ73_13905 | Protease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
| zapD | mreD | UZ73_13420 | UZ73_13550 | Cell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.549 |
| zapD | pmbA | UZ73_13420 | UZ73_13905 | Cell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | Peptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.466 |