STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycgRHypothetical protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility. (246 aa)    
Predicted Functional Partners:
fliS
Flagellar protein FliS; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.885
ALO39716.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.839
ALO39574.1
Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
    0.822
ALO38435.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.811
ALO39571.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.801
fliM
Flagellar motor switch protein FliM; With FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.800
ALO38497.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.770
motB
Flagellar motor protein MotB; With MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.745
ALO39565.1
Flagellar protein FliJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.742
ALO40450.1
Flagellar hook-length control protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.737
Your Current Organism:
Alcaligenes faecalis
NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Achromobacter sp. ATCC8750, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.