node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALO37061.1 | ALO38751.1 | UZ73_01565 | UZ73_11080 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | 0.779 |
ALO37061.1 | ALO39454.1 | UZ73_01565 | UZ73_14965 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.658 |
ALO37061.1 | ALO39455.1 | UZ73_01565 | UZ73_14970 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |
ALO37061.1 | ALO39456.1 | UZ73_01565 | UZ73_14975 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoadenosine phosphosulfate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.948 |
ALO37061.1 | cobA-2 | UZ73_01565 | UZ73_11070 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.987 |
ALO37061.1 | cysA | UZ73_01565 | UZ73_01480 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | 0.492 |
ALO37061.1 | cysI | UZ73_01565 | UZ73_11075 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.966 |
ALO38751.1 | ALO37061.1 | UZ73_11080 | UZ73_01565 | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.779 |
ALO38751.1 | ALO38922.1 | UZ73_11080 | UZ73_12025 | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Thiosulfate transporter subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.967 |
ALO38751.1 | ALO39454.1 | UZ73_11080 | UZ73_14965 | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.981 |
ALO38751.1 | ALO39455.1 | UZ73_11080 | UZ73_14970 | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.988 |
ALO38751.1 | ALO39456.1 | UZ73_11080 | UZ73_14975 | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Phosphoadenosine phosphosulfate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
ALO38751.1 | ALO40471.1 | UZ73_11080 | UZ73_16760 | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Sulfite oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.686 |
ALO38751.1 | cobA-2 | UZ73_11080 | UZ73_11070 | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.956 |
ALO38751.1 | cysA | UZ73_11080 | UZ73_01480 | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | 0.839 |
ALO38751.1 | cysI | UZ73_11080 | UZ73_11075 | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.999 |
ALO38922.1 | ALO38751.1 | UZ73_12025 | UZ73_11080 | Thiosulfate transporter subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADP oxidoreductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | 0.967 |
ALO38922.1 | ALO39454.1 | UZ73_12025 | UZ73_14965 | Thiosulfate transporter subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
ALO38922.1 | ALO39455.1 | UZ73_12025 | UZ73_14970 | Thiosulfate transporter subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
ALO38922.1 | ALO39456.1 | UZ73_12025 | UZ73_14975 | Thiosulfate transporter subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoadenosine phosphosulfate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.934 |